Which drugs are nitrogen mustards?
The nitrogen mustard class includes mechlorethamine, cyclophosphamide, 4-hydroperoxy cyclophosphamide, ifosfamide, chlorambucil, and melphalan. These drugs all share a common bischloroethyl group attached to nitrogen and a substituted “R” group that provides drug specificity (Fig. 57.3).
What is the chemical makeup of mustard gas?
The chemical formula for mustard gas is C4H8Cl2S. The chemical structure is Cl-CH2-CH2-S-CH2CH2-Cl.
Is mustard gas a chemotherapy?
Edward and Helen Krumbhaar during World War I. By World War II, at least two dozen medical researchers transformed mustard agents into cancer chemotherapy. In the 1940s, sulfur mustard, commonly called mustard gas, and nitrogen mustard, a derivative of mustard gas, became a new form of cancer treatment.
What is the term used for the nitrogen mustard anticancer agents?
In some cases, health care professionals may use the trade name Mustargen or other names Nitrogen Mustard, Mustine, and Mechlorethamine Hydrochloride when referring to the generic drug name Mechlorethamine. Drug type: Nitrogen Mustard is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.
What is vinblastine used for?
Vinblastine is used to treat Hodgkin’s disease, certain types of lymphoma, testicular cancer, breast cancer, choriocarcinoma (a type of uterine cancer), Kaposi’s sarcoma, and Letterer-Siwe disease. Vinblastine is often used in combination with other cancer medications.
What is 6 mercaptopurine used for?
Mercaptopurine is used alone or with other chemotherapy drugs to treat acute lymphocytic leukemia (ALL; also called acute lymphoblastic leukemia and acute lymphatic leukemia; a type of cancer that begins in the white blood cells). Mercaptopurine is in a class of medications called purine antagonists.
What is the chemical formula of phosgene?
COCl2
Phosgene/Formula
Who is the father of chemotherapy?
Paul Ehrlich: Nobel laureate and father of modern chemotherapy.
Who created chemotherapy?
Paul Ehrlich (1854-1915): founder of chemotherapy and pioneer of haematology, immunology and oncology.
How is vinblastine made?
Vinblastine belongs to a class of chemotherapy drugs called alkaloids. Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea).
What is vinblastine and curcumin?
Abstract. Background: Curcumin, a major component of curry powder, which is a natural polyphenol product extracted from rhizoma curcumae longae, interacts with a specific binding site on microtubules. Vinblastine is an antitumor drug that induces microtubule depolymerization.
